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SIGLEC5 anticorps
SIGLEC5
Reactivité: Humain
ICFC
Hôte: Souris
Monoclonal
1A5
unconjugated
N° du produit ABIN2664288
Détail du produit anti-SIGLEC5 anticorps
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Antigène
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SIGLEC5
(Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
Reactivité
Toutes les réactivités sur SIGLEC5 Anticorps
Humain
Hôte
Toutes les hôtes sur SIGLEC5 Anticorps
Souris
Clonalité
Toutes les clonalités sur SIGLEC5 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers SIGLEC5 Anticorps
Cet anticorp SIGLEC5 est non-conjugé
Application
Tous les applications à travers SIGLEC5 Anticorps.
Intracellular Flow Cytometry (ICFC)
Réactivité croisée
Chimpanzé, Bonobo, Gorilla
Purification
The antibody was purified by affinity chromatography.
Clone
1A5
Isotype
IgG1 kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur SIGLEC5
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Antigène
SIGLEC5
(Sialic Acid Binding Ig-Like Lectin 5 (SIGLEC5))
Autre désignation
CD170 (SIGLEC5 Produits )
Synonymes
anticorps CD170, anticorps CD33L2, anticorps OB-BP2, anticorps OBBP2, anticorps SIGLEC-5, anticorps sialic acid binding Ig like lectin 5, anticorps sialic acid-binding Ig-like lectin 5, anticorps sialic acid binding Ig-like lectin 5, anticorps SIGLEC5, anticorps LOC100597560, anticorps Siglec5
Sujet
CD170, also known as Siglec-5, is a single pass transmembrane protein member of the immunoglobulin superfamily. On the cell surface, CD170 forms a 140 kD dimer. The cytoplasmic domain of Siglec-5 contains two ITIM motifs that recruit the tyrosine-phosphatases SHP-1 and SHP-2 after tyrosine-phosphorylation, which in turn results in the inhibition of cell signaling. Siglec-5 is expressed by granulocytes, monocytes/macrophages, subsets of lymphocytes, and a subset of activated dendritic cells. Siglec-5 binds α2,3- and α2,6-linked sialic acid as well as glycophorin A, and is involved in cell adhesion.
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