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ITGA2 anticorps
ITGA2
Reactivité: Humain
FACS, IHC, CoSt
Hôte: Souris
Monoclonal
P1E6-C5
unconjugated
N° du produit ABIN2664741
Détail du produit anti-ITGA2 anticorps
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Antigène
Voir toutes ITGA2 Anticorps
ITGA2
(Integrin alpha 2 (ITGA2))
Reactivité
Toutes les réactivités sur ITGA2 Anticorps
Humain
Hôte
Toutes les hôtes sur ITGA2 Anticorps
Souris
Clonalité
Toutes les clonalités sur ITGA2 Anticorps
Monoclonal
Conjugué
Tous les conjugués à travers ITGA2 Anticorps
Cet anticorp ITGA2 est non-conjugé
Application
Tous les applications à travers ITGA2 Anticorps.
Flow Cytometry (FACS), Immunohistochemistry (IHC), Co-Stimulation (CoSt)
Purification
The antibody was purified by affinity chromatography.
Clone
P1E6-C5
Isotype
IgG1 kappa
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Alternatives
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
4 °C
Stockage commentaire
The antibody solution should be stored undiluted between 2°C and 8°C.
Détails sur ITGA2
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Antigène
ITGA2
(Integrin alpha 2 (ITGA2))
Autre désignation
CD49b (ITGA2 Produits )
Synonymes
anticorps BR, anticorps CD49B, anticorps GPIa, anticorps HPA-5, anticorps VLA-2, anticorps VLAA2, anticorps DX5, anticorps integrin subunit alpha 2, anticorps integrin alpha 2, anticorps ITGA2, anticorps Itga2
Sujet
CD49b is a 170 kD transmembrane protein, also known as α2 integrin, VLA-2 α chain, Integrin α2 and GPIa. It associates with CD29 (β1 integrin) to form VLA-2, a collagen and laminin receptor on many cell types including monocytes, platelets, activated T cells, megakaryocytes, neuronal cells, epithelial cells, and osteoclasts. CD49b has been reported to interact with F-actin and matrix metalloproteinase 1. CD49b is a platelet alloantigen and has been associated with neonatal alloimmune thrombocytopenia. Deficiencies in this protein have been associated with hemorrhagic disorders.
Pathways
CXCR4-mediated Signaling Events , Smooth Muscle Cell Migration , Integrin Complex
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