DLL1 anticorps

N° du produit ABIN2664930

Cet anticorps Souris Monoclonal détecte spécifiquement DLL1 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour DLL1 anticorps (ABIN2664930)

Antigène: DLL1 (delta-Like 1 (DLL1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DLL1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: MHD1-314

Détail du produit anti-DLL1 anticorps

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur DLL1

Antigène: DLL1 (delta-Like 1 (DLL1))

Autre désignation: delta-Like Protein 1

Sujet: Delta-like protein 1 is a type I transmembrane protein. The mature form consist of an extracellular domain of 528 amino acids (aa) that contain a DSL domain and eight tandem EGF repeats, the transmembrane region is 23 aa long and has a 155 aa cytoplasmic domain. After the binding of Notch receptors, the extracellular and cytoplasmic domains are cleaved, and the later is translocated into the cell nucleus to regulate gene expression. Delta-like protein 1 is expressed in heart and pancreas and in a lower amount in brain and muscle. During fetal life, it is transiently expressed during gastrulation and early organogenesis and its expression remains through adult life in hematopoietic tissues and the cortico-medullary region of the thymus.

Pathways: Signalisation Notch, Stem Cell Maintenance