Oct-2 anticorps

N° du produit ABIN2665310

Cet anticorps anti-Oct-2 Monoclonal Souris (Clone 2B10B19) (ABIN2665310) détecte spécifiquement Oct-2 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Oct-2 anticorps (ABIN2665310)

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Oct-2 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 2B10B19

Détail du produit anti-Oct-2 anticorps

Réactivité croisée: Souris

Purification: The antibody was purified by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Oct-2

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Autre désignation: Oct-2

Sujet: OCT2 is a member of the POU family of transcription factors that was found to be expressed predominantly in B lymphocytes, activated T lymphocytes, and neuronal cells. OCT2 binds to the conserved octamer DNA element, ATGCAAAT, which was discovered in the promoters and enhancers of immunoglobulin (Ig) genes. In addition to regulating Ig gene expression, OCT2 controls several B cell specific genes required for proliferation and differentiation, such as CD20, CD36, and CD79a. OCT2 was found to have different isoforms produced by alternative splicing. The OCT2 isoforms exert distinct functional activities and can act as transcriptional activators or repressors.