Oct-2 anticorps (AA 11-100)

N° du produit ABIN737316

Détail du produit anti-Oct-2 anticorps

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Épitope: AA 11-100

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oct-2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse OCT2

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Oct-2 (ABIN737316)

Zhou, Bi, Gao, An, Chen, Chen: "Macrophage polarization in human gingival tissue in response to periodontal disease." dans: Oral diseases, Vol. 25, Issue 1, pp. 265-273, (2019) (PubMed).

Xu, Zhu, Chan, Lu, Shen, Gillies, Zhou: "The Altered Renal and Hepatic Expression of Solute Carrier Transporters (SLCs) in Type 1 Diabetic Mice." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0120760, (2015) (PubMed).

Détails sur Oct-2

Antigène: Oct-2 (POU2F2) (POU domain, class 2, transcription factor 2 (POU2F2))

Autre désignation: 2-Oct (POU2F2 Produits)

Synonymes: anticorps OCT2, anticorps OTF2, anticorps Oct-2, anticorps Pou2f2, anticorps Oct2a, anticorps Oct2b, anticorps Otf-2, anticorps Otf2, anticorps 2-Oct, anticorps Oct2, anticorps POU class 2 homeobox 2, anticorps POU domain, class 2, transcription factor 2, anticorps solute carrier family 22 (organic cation transporter), member 2, anticorps POU2F2, anticorps Pou2f2, anticorps SLC22A2

Sujet:

Synonyms: Otf2, Oct-2, Oct2a, Oct2b, Otf-2, POU domain, class 2, transcription factor 2, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, Octamer-binding protein 2, Octamer-binding transcription factor 2, Pou2f2, Oct2

Background: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform OCT2.5 activates the U2 small nuclear RNA (snRNA) promoter. Isoforms OCT2.1, OCT2.2 and OCT2.3 activate octamer-containing promoters. Isoforms OCT2.4 and OCT2.5 repress some promoters and activate others. Isoform OCT2.7 is unable to bind to the octamer motif, but can still activate the beta-casein gene promoter at low levels.

ID gène: 18987

UniProt: Q00196