c-FOS anticorps

N° du produit ABIN2666052

Cet anticorps Lapin Polyclonal détecte spécifiquement c-FOS dans FACS. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour c-FOS anticorps (ABIN2666052)

Antigène: c-FOS (c-Fos) (c-Fos)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp c-FOS est non-conjugé

Application: Flow Cytometry (FACS)

Clone: Poly6414

Détail du produit anti-c-FOS anticorps

Réactivité croisée (Details): Mouse (very weak)

Purification: The antibody was purified by antigen-affinity chromatography.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Upon receipt, store at -20°C.

Détails sur c-FOS

Antigène: c-FOS (c-Fos) (c-Fos)

Autre désignation: C-Fos

Sujet: The c-fos protein, also known as FBJ murine viral (v-fos) oncogene homolog , is a 62 kD cellular oncogene. The c-fos protein contains a bZIP region with a DNA-binding domain and a leucine zipper domain. Together with c-jun, c-jun proteins form the heterodimeric AP-1 complex that binds to the TRE elements of cellular and viral genes including collagenase, interleukin 2, stromelysin, SV40 and polyoma among others. c-fos is expressed in a variety of normal adult tissues and has been implicated as a critical transcription factor for skeletal formation and maintenance. This transcription factor is modified by phosphorylation by a number of upstream kinases and has been shown to interact with a variety of other proteins involved in transcriptional regulation. c-fos has been implicated in the development of fibrous bone dysplasia and osteosarcoma. The c-fos protein has been shown to interact with a variety of other proteins including c-jun, TFIID, NCOA2, NFAT1, CHOP, ELK1, SRC1, and ETS1.

Pathways: S100 Proteins