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IRF9 anticorps

IRF9 Reactivité: Humain FACS Hôte: Souris Monoclonal 5A3A39 unconjugated
N° du produit ABIN2666230
  • Antigène Voir toutes IRF9 Anticorps
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Reactivité
    • 48
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 6
    • 1
    Souris
    Clonalité
    • 45
    • 4
    Monoclonal
    Conjugué
    • 25
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IRF9 est non-conjugé
    Application
    • 37
    • 15
    • 13
    • 13
    • 10
    • 9
    • 8
    • 3
    • 2
    • 2
    • 2
    Flow Cytometry (FACS)
    Purification
    Affinity purified.
    Clone
    5A3A39
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product IRF9 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Upon receipt, store undiluted 2°C and 8°C.
  • Antigène
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Autre désignation
    IRF9 (IRF9 Produits)
    Synonymes
    anticorps IRF-9, anticorps ISGF3, anticorps ISGF3G, anticorps p48, anticorps zgc:92097, anticorps Irf-9, anticorps Isgf3g, anticorps interferon regulatory factor 9, anticorps IRF9, anticorps irf9, anticorps Irf9
    Sujet
    IRF9 is a member of the IRF family of transcription factors and plays an important role in IFN signaling pathways and anti-viral immune responses. Type I and type III interferon stimulation induces phosphorylation and heterodimerization of STAT1 and STAT2. The activated STAT1:STAT2 heterodimer recruits IRF9 and forms a heterotrimeric complex termed IFN-stimulated gene factor 3 (ISGF3). The ISGF3 complex, in turn, translocates to the nucleus and transactivates IFN-inducible genes. The IRF9 protein in the ISGF3 complex is responsible for the recognition of IFN-stimulated response elements (ISRE). Mice lacking IRF9 fail to induce the expression of IFN regulated genes in response to type I interferon stimulation, indicating that IRF9 is crucial in mediating interferon signaling.
    Pathways
    Signalistation JAK/STAT, Interferon-gamma Pathway, Hepatitis C
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