CENPA anticorps (pSer18)

N° du produit ABIN2668362

Cet anticorps Lapin Polyclonal détecte spécifiquement CENPA dans WB, IF, ICC et DB. Il présente une réactivité avec des échantillons de Humain.Il a été cité dans 1 publication.

Aperçu rapide pour CENPA anticorps (pSer18) (ABIN2668362)

Antigène: CENPA (Centromere Protein A (CENPA))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CENPA est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Dot Blot (DB)

Détail du produit anti-CENPA anticorps

Épitope: pSer18

Fonction: CENP-A phospho Ser18 antibody (pAb)

Purification: Affinity Purified

Immunogène: This antibody was raised against a synthetic peptide containing phosphorylated serine 16 and 18 of human CENP-A.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100 dilution WB: 1:100 - 1:500 dilution The addition of 0.05 % Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-CENPA (ABIN2668362)

Logsdon, Barrey, Bassett, DeNizio, Guo, Panchenko, Dawicki-McKenna, Heun, Black: "Both tails and the centromere targeting domain of CENP-A are required for centromere establishment." dans: The Journal of cell biology, Vol. 208, Issue 5, pp. 521-31, (2015) (PubMed).

Détails sur CENPA

Antigène: CENPA (Centromere Protein A (CENPA))

Autre désignation: CENP-A

Sujet: CENP-A (Centromere Protein A) is a Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. It is required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. Recently, phosphorylation of CENP-A on Ser16 and Ser18 was reported and found to be important for chromosome segregation during mitosis.

Poids moléculaire: 16 kDa

ID gène: 1058

NCBI Accession: NP_001800

Pathways: Chromatin Binding, Maintenance of Protein Location