RECQL2 anticorps

N° du produit ABIN2668372

Il existe 1 publication pour ce produit. L’anticorps anti-RECQL2 Monoclonal Souris est utilisé pour la détection de RECQL2 dans des échantillons de Humain. Il a été validé pour WB, IHC, IF et ICC.

Aperçu rapide pour RECQL2 anticorps (ABIN2668372)

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp RECQL2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 195C

Détail du produit anti-RECQL2 anticorps

Fonction: WRN antibody (mAb) (Clone 195C)

Purification: Protein G Chromatography

Immunogène: This WRN antibody was raised against a recombinant protein corresponding to amino acids 1072 - 1432 of human WRN.

Isotype: IgG1

Information d'application

Indications d'application: ICC/IF: 0.5 μg/mL dilution IHC(P): User optimization required WB: 0.5 - 2 μg/mL dilution

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Références pour anticorps anti-RECQL2 (ABIN2668372)

Opresko, Calvo, von Kobbe: "Role for the Werner syndrome protein in the promotion of tumor cell growth." dans: Mechanisms of ageing and development, Vol. 128, Issue 7-8, pp. 423-36, (2007) (PubMed).

Détails sur RECQL2

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Autre désignation: WRN

Sujet: WRN protein is a RECQ helicase that contains 3' to 5' helicase activity and DNA-dependent ATPase activity. WRN takes part in many processes, including DNA replication, recombination, repair, and telomere maintenance. Mutations in the gene encoding WRN cause an autosomal recessive segmental progeria called Werner syndrome (WS). WS patients prematurely develop atrophic skin, thin gray hair, osteoporosis, type II diabetes, cataracts, arteriosclerosis and cancer.

Poids moléculaire: 162 kDa

ID gène: 7486

NCBI Accession: NP_000544

Pathways: Réparation de l'ADN