RECQL2 anticorps

N° du produit ABIN7254655

Cet anticorps anti-RECQL2 Polyclonal Lapin (ABIN7254655) détecte spécifiquement RECQL2 dans ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour RECQL2 anticorps (ABIN7254655)

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RECQL2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RECQL2 anticorps

Attributs du produit: Polyclonal Antibody

Purification: Antigen affinity purification

Immunogène: Synthetic peptide of human WRN

Isotype: IgG

Information d'application

Indications d'application: IHC 1:30-1:150, ELISA 1:5000-1:10000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.8 mg/mL

Buffer: PBS with 0.05 % Sodium azide and 40 % Glycerol, pH 7.4

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur RECQL2

Antigène: RECQL2 (WRN) (Werner syndrome RecQ like helicase (WRN))

Autre désignation: WRN

Sujet: This gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism, including transcription, replication, recombination, and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity, and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70/80 heterodimer in DNA end processing, this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by premature aging.

UniProt: Q14191

Pathways: Réparation de l'ADN