CENPE anticorps

N° du produit ABIN2668581

Cet anticorps Souris Monoclonal détecte spécifiquement CENPE dans ICC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour CENPE anticorps (ABIN2668581)

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CENPE est non-conjugé

Application: Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: 1H12

Détail du produit anti-CENPE anticorps

Fonction: CENP-E antibody (mAb) (Clone 1H12)

Purification: Protein G Chromatography

Immunogène: This CENP-E antibody was raised against full-length human CENP-E protein.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1 μg/mL dilution This CENP-E antibody can be used in Western blot to detect CENP-E if the protein has been first enriched by immunoprecipitation.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur CENPE

Antigène: CENPE (Centromere Protein E, 312kDa (CENPE))

Autre désignation: CENP-E

Sujet: Centrosome-associated protein E (CENP-E) is a kinesin-like protein and an integral component of kinetochore fibers that link centromeres to spindle microtubules. CENP-E localizes to kinetochores throughout all phases of mitotic chromosome movement. After the onset of anaphase it is released, and by telophase becomes bound to interzonal microtubules of the mitotic spindle. It is likely that CENP-E serves as a chromosome motor during anaphase.

Poids moléculaire: 320 kDa

NCBI Accession: NP_001804

Pathways: M Phase, Maintenance of Protein Location