Aurora Kinase B anticorps (C-Term)

N° du produit ABIN2668672

L’anticorps anti-Aurora Kinase B Polyclonal Lapin est utilisé pour la détection de Aurora Kinase B dans des échantillons de Humain et Souris. Il a été validé pour WB, IF et ICC.

Aperçu rapide pour Aurora Kinase B anticorps (C-Term) (ABIN2668672)

Antigène: Aurora Kinase B (AURKB)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aurora Kinase B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-Aurora Kinase B anticorps

Épitope: C-Term

Fonction: Aurora B antibody (pAb)

Purification: Unpurified

Immunogène: This Aurora B antibody was raised against a peptide including the C-terminus of human Aurora B.

Information d'application

Indications d'application: ICC/IF: 1:200 - 1:1,000 dilution WB: 1:500 - 1:5,000 dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit serum containing 30 % glycerol and 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions,Keep all reagents on ice when not in storage

Stock: -20 °C

Stockage commentaire: Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Date de péremption: 24 months

Détails sur Aurora Kinase B

Antigène: Aurora Kinase B (AURKB)

Autre désignation: Aurora B

Sujet: Aurora B (Aurora Kinase B, AurB, ARK2) is a Ser/Thr kinase that is part of the chromosomal passenger complex that associates with chromosomes and is an important regulator of mitosis and meiosis. Aurora B becomes concentrated at the centromere during the onset of mitosis, but relocates to the spindle midzone during anaphase. Aurora B phosphorylates a number of substrates, including INCENP, CENP-A, and Histone H3. Misregulation of Aurora B activity can lead to chromosome instability and is implicated in a number of cancers.

Poids moléculaire: 49 kDa

ID gène: 9212

NCBI Accession: NP_004208

Pathways: TCR Signaling, Cycle Cellulaire, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades