Lamin A/C anticorps (AA 430-545)

N° du produit ABIN2668844

Cet anticorps anti-Lamin A/C est un anticorps Souris Monoclonal détectant Lamin A/C dans WB, IF et ICC. Adapté pour Humain, Souris, Rat, Singe et Hamster. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour Lamin A/C anticorps (AA 430-545) (ABIN2668844)

Antigène: Lamin A/C (LMNA)

Reactivité: Humain, Souris, Rat, Singe, Hamster

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Lamin A/C est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: 3A6-4C11

Détail du produit anti-Lamin A/C anticorps

Épitope: AA 430-545

Purification: Culture Supernatant

Immunogène: This Lamin A/C antibody was raised against a recombinant protein corresponding to amino acids 430-545 of human Lamin A.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1 μg/μL

Buffer: Cell culture supernatant containing mouse IgG, 30 % glycerol, 0.035 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Stock: -20 °C

Stockage commentaire: Antibodies in solution can be stored at -20 °C for 2 years.

Date de péremption: 6 months

Références pour anticorps anti-Lamin A/C (ABIN2668844)

Gesson, Rescheneder, Skoruppa, von Haeseler, Dechat, Foisner: "A-type lamins bind both hetero- and euchromatin, the latter being regulated by lamina-associated polypeptide 2 alpha." dans: Genome research, Vol. 26, Issue 4, pp. 462-73, (2016) (PubMed).

Kim, Zheng: "Generation and characterization of a conditional deletion allele for Lmna in mice." dans: Biochemical and biophysical research communications, Vol. 440, Issue 1, pp. 8-13, (2013) (PubMed).

Eckersley-Maslin, Bergmann, Lazar, Spector: "Lamin A/C is expressed in pluripotent mouse embryonic stem cells." dans: Nucleus (Austin, Tex.), Vol. 4, Issue 1, pp. 53-60, (2013) (PubMed).

Détails sur Lamin A/C

Antigène: Lamin A/C (LMNA)

Autre désignation: Lamin A/C

Poids moléculaire: 75 kDa

ID gène: 4000

Pathways: Apoptose, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus