C3a anticorps

N° du produit ABIN2688860

Détail du produit anti-C3a anticorps

Antigène: C3a (Complement Fragment 3a (C3a))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp C3a est non-conjugé

Application: ELISA

Marque: BD Pharmingen™

Attributs du produit: The purified I87-1162 antibody reacts with the mouse C3a protein. The I87-1162 antibody is specific for a neoepitope exposed in mouse C3a/C3adesArg and does not cross-react with mouse C3. This capacity makes antibody I87-1162 a preferential capture antibody for direct detection of mouse C3a from plasma or serum samples in an ELISA sandwich assay. Anaphylatoxin C3a is a bioactive cleavage product released from plasma component C3 during complement activation and is involved in mediation of a variety of cellular immune responses, as well as being a potent pro-inflammatory agent. The release of this cleavage product is a reliable indicator of in vivo or in vitro complement activation. Representative Mouse C3a standard curve. The curve was generated by a sandwich ELISA using the purified I87-1162 antibody (Cat. No. 558250) as capture antibody, doubling dilutions of purified mouse C3a protein (Cat. No. 558618) as standard, and biotinylated I87-419 antibody (Cat. No. 558251) as detection antibody. The standard curve is displayed as the concentration of purified mouse C3a in ng/mL versus the microwell absorbance.

BD Pharmingen™ Purified Rat Anti-Mouse C3a - Purified - Clone I87-1162 - Isotype Rat IgG1, κ - Reactivity Ms - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: ELISA) Hugli T.E. Structure and function of the anaphylatoxins.

Clone: I87

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-C3a (ABIN2688860)

Hugli: "Structure and function of C3a anaphylatoxin." dans: Current topics in microbiology and immunology, Vol. 153, pp. 181-208, (1990) (PubMed).

Hugli: "Structure and function of the anaphylatoxins." dans: Springer seminars in immunopathology, Vol. 7, Issue 2-3, pp. 193-219, (1984) (PubMed).

Détails sur C3a

Antigène: C3a (Complement Fragment 3a (C3a))

Autre désignation: C3a (C3a Produits)

Synonymes: anticorps AHUS5, anticorps ARMD9, anticorps ASP, anticorps C3a, anticorps C3b, anticorps CPAMD1, anticorps AI255234, anticorps HSE-MSF, anticorps Plp, anticorps C3d, anticorps complement C3, anticorps complement component 3, anticorps C3

Pathways: Système du Complément