CD4 anticorps

N° du produit ABIN2689220

Cet anticorps Souris Monoclonal détecte spécifiquement CD4 dans FACS. Il présente une réactivité avec des échantillons de Macaque rhésus, Cynomolgus et Babouin. Il a été cité dans 4+ publications.

Aperçu rapide pour CD4 anticorps (ABIN2689220)

Antigène: CD4

Reactivité: Macaque rhésus, Cynomolgus, Babouin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: L200

Détail du produit anti-CD4 anticorps

Attributs du produit: The L200 antibody reacts with the human form of the 56 kDa transmembrane glycoprotein, CD4, present on the T-helper/inducer subset of normal human donor peripheral blood lymphocytes. L200 antibody also cross-reacts with a subset of CD3-positive peripheral blood lymphocytes, but not monocytes, of both rhesus and cynomolgus macaque monkeys. Cross-reactivity on both lymphocytes and monocytes (weak) of baboon is also observed. The distribution on lymphocytes is similar for both human and monkey, with the majority of CD4-positive lymphocytes being CD8-negative and lacking reactivity with antibodies to B- or NK-cell markers. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature. Profile of anti-CD4 reactivity on peripheral blood lymphocytes of rhesus macaque (Macaca mulatta) analyzed by flow cytometry

BD Pharmingen™ Purified Mouse Anti-Human CD4 - Purified - Clone L200 - Isotype Mouse IgG1, κ - Reactivity Bab, Cyno, Rhe - 0.1 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-CD4 (ABIN2689220)

Verdier, Aujoulat, Condevaux, Descotes: "Determination of lymphocyte subsets and cytokine levels in cynomolgus monkeys." dans: Toxicology, Vol. 105, Issue 1, pp. 81-90, (1996) (PubMed).

Jacobsen, Aasted, Broe, Petersen: "Reactivities of 20 anti-human monoclonal antibodies with leucocytes from ten different animal species." dans: Veterinary immunology and immunopathology, Vol. 39, Issue 4, pp. 461-6, (1994) (PubMed).

Indzhiia, Yakovleva, Overbaugh, Licciardi, Chikobava, Klotz, Torres, Indzhiia, Lapin, Clark: "Baboon T cell lymphomas expressing the B cell-associated surface proteins CD40 and Bgp95." dans: Journal of clinical immunology, Vol. 12, Issue 3, pp. 225-36, (1992) (PubMed).

Powell, McClure, Anderson, Fultz, Sell, Ahmed-Ansari: "Phenotypic and functional differences in NK and LAK cells in the peripheral blood of sooty mangabeys and rhesus macaques." dans: Cellular immunology, Vol. 124, Issue 1, pp. 107-18, (1989) (PubMed).

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events