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Integrin Alpha2b anticorps

CD41 Reactivité: Souris FACS, IHC (fro), IP, CyTox Hôte: Rat Monoclonal MWReg30 unconjugated
N° du produit ABIN2689249
  • Antigène Voir toutes Integrin Alpha2b (CD41) Anticorps
    Integrin Alpha2b (CD41)
    Reactivité
    • 125
    • 33
    • 21
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 84
    • 43
    • 24
    Rat
    Clonalité
    • 105
    • 40
    • 1
    Monoclonal
    Conjugué
    • 59
    • 17
    • 13
    • 12
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Integrin Alpha2b est non-conjugé
    Application
    • 105
    • 48
    • 32
    • 28
    • 21
    • 19
    • 13
    • 13
    • 10
    • 10
    • 8
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Cytotoxicity Test (CyTox)
    Marque
    BD Pharmingen™
    Attributs du produit
    The MWReg30 antibody reacts with glycoprotein (gp) IIb, also called integrin αIIb chain (CD41), that associates with integrin β3 chain (gpIIIa or CD61) to form the gpIIb/IIIa (CD41/CD61) complex. CD41/CD61 is expressed on platelets, megakaryocytes, and early hematopoietic progenitors. The integrin complex binds to fibrinogen, fibronectin, vitronectin, von Willebrand factor, and thrombospondin. It is important for platelet adhesion and aggregation, and it may play a role in osteolytic tumor metastasis. This antibody is routinely tested by flow cytometric analysis. Other applications were tested during antibody development only or reported in the literature.

    BD Pharmingen™ Purified Rat Anti-Mouse CD41 - Purified - Clone MWReg30 - Isotype Rat IgG1, κ - Reactivity Ms - 0.5 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Mouse Platelets
    Clone
    MWReg30
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD41 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store undiluted at 4°C.
  • Bakewell, Nestor, Prasad, Tomasson, Dowland, Mehrotra, Scarborough, Kanter, Abe, Phillips, Weilbaecher: "Platelet and osteoclast beta3 integrins are critical for bone metastasis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14205-10, (2003) (PubMed).

    Ferkowicz, Starr, Xie, Li, Johnson, Shelley, Morrison, Yoder: "CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo." dans: Development (Cambridge, England), Vol. 130, Issue 18, pp. 4393-403, (2003) (PubMed).

    Nieswandt, Echtenacher, Wachs, Schröder, Gessner, Schmidt, Grau, Männel: "Acute systemic reaction and lung alterations induced by an antiplatelet integrin gpIIb/IIIa antibody in mice." dans: Blood, Vol. 94, Issue 2, pp. 684-93, (1999) (PubMed).

    Kieffer, Phillips: "Platelet membrane glycoproteins: functions in cellular interactions." dans: Annual review of cell biology, Vol. 6, pp. 329-57, (1991) (PubMed).

    Phillips, Charo, Scarborough: "GPIIb-IIIa: the responsive integrin." dans: Cell, Vol. 65, Issue 3, pp. 359-62, (1991) (PubMed).

  • Antigène
    Integrin Alpha2b (CD41)
    Autre désignation
    CD41 (CD41 Produits)
    Synonymes
    anticorps AI172977, anticorps CD41, anticorps CD41B, anticorps GpIIb, anticorps alphaIIb, anticorps BDPLT16, anticorps BDPLT2, anticorps GP2B, anticorps GPIIb, anticorps GT, anticorps GTA, anticorps HPA3, anticorps integrin alpha 2b, anticorps integrin subunit alpha 2b, anticorps Itga2b, anticorps ITGA2B
    Sujet
    Synonyms: Integrin α IIb chain
    Pathways
    Integrin Complex
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