C5AR1 anticorps

N° du produit ABIN2689428

Détail du produit anti-C5AR1 anticorps

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp C5AR1 est non-conjugé

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Marque: BD Pharmingen™

Attributs du produit: The human C5a receptor (C5aR) is expressed on granulocytes, monocytes, macrophages mast cells human cell lines of myeloid origin, and certain cell types in several organs, including dendritic cells of secondary lymphoid organs, liver hepatocytes, lung bronchial and alveolar epithelial cells, lung vascular smooth muscle, endothelial cells astrocytes, microglia, and fibroblast-like cells of the brain. The C85-2506 is a rabbit monoclonal antibody generated by fusion of splenocytes from rabbits immunized with human C5aR peptides and the rabbit fusion partner 240E-1. C85-2506 staining on dendritic cells and granulocytes of human tonsil paraffin sections.

BD Pharmingen™ Purified Rabbit Anti-Human CD88 - Purified - Clone C85-2506 - Isotype Rabbit IgG - Reactivity Hu - 1 mL

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Clone: C85

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Aqueous buffered solution containing BSA, goat serum, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C.

Références pour anticorps anti-C5AR1 (ABIN2689428)

Fayyazi, Sandau, Duong, Götze, Radzun, Schweyer, Soruri, Zwirner: "C5a receptor and interleukin-6 are expressed in tissue macrophages and stimulated keratinocytes but not in pulmonary and intestinal epithelial cells." dans: The American journal of pathology, Vol. 154, Issue 2, pp. 495-501, (1999) (PubMed).

Paradisis, Campbell, Barnum: "Elevated complement C5a receptor expression on neurons and glia in astrocyte-targeted interleukin-3 transgenic mice." dans: Glia, Vol. 24, Issue 3, pp. 338-45, (1999) (PubMed).

Nataf, Davoust, Barnum: "Kinetics of anaphylatoxin C5a receptor expression during experimental allergic encephalomyelitis." dans: Journal of neuroimmunology, Vol. 91, Issue 1-2, pp. 147-55, (1998) (PubMed).

Stahel, Frei, Eugster, Fontana, Hummel, Wetsel, Ames, Barnum: "TNF-alpha-mediated expression of the receptor for anaphylatoxin C5a on neurons in experimental Listeria meningoencephalitis." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 159, Issue 2, pp. 861-9, (1997) (PubMed).

Morelli, Larregina, Chuluyán, Kolkowski, Fainboim: "Expression and modulation of C5a receptor (CD88) on skin dendritic cells. Chemotactic effect of C5a on skin migratory dendritic cells." dans: Immunology, Vol. 89, Issue 1, pp. 126-34, (1996) (PubMed).

Füreder, Agis, Willheim, Bankl, Maier, Kishi, Müller, Czerwenka, Radaszkiewicz, Butterfield, Klappacher, Sperr, Oppermann, Lechner, Valent: "Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 155, Issue 6, pp. 3152-60, (1995) (PubMed).

Haviland, McCoy, Whitehead, Akama, Molmenti, Brown, Haviland, Parks, Perlmutter, Wetsel: "Cellular expression of the C5a anaphylatoxin receptor (C5aR): demonstration of C5aR on nonmyeloid cells of the liver and lung." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 154, Issue 4, pp. 1861-9, (1995) (PubMed).

Spieker-Polet, Sethupathi, Yam, Knight: "Rabbit monoclonal antibodies: generating a fusion partner to produce rabbit-rabbit hybridomas." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 20, pp. 9348-52, (1995) (PubMed).

Wetsel: "Expression of the complement C5a anaphylatoxin receptor (C5aR) on non-myeloid cells." dans: Immunology letters, Vol. 44, Issue 2-3, pp. 183-7, (1995) (PubMed).

Détails sur C5AR1

Antigène: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Autre désignation: CD88 (C5AR1 Produits)

Synonymes: anticorps C5A, anticorps C5AR, anticorps C5R1, anticorps CD88, anticorps C5aR, anticorps C5r1, anticorps Cd88, anticorps D7Msu1, anticorps GPR77, anticorps complement C5a receptor 1, anticorps complement component 5a receptor 1, anticorps C5AR1, anticorps C5ar1, anticorps c5ar1

Sujet: Synonyms: C5a Receptor

Pathways: Système du Complément