CD3 anticorps

N° du produit ABIN2704232

Cet anticorps anti-CD3 est un anticorps Souris Monoclonal détectant CD3 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD3 anticorps (ABIN2704232)

Antigène: CD3

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD3 est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: OKT3

Détail du produit anti-CD3 anticorps

Fonction: CD3 Unconjugated Antibody

Attributs du produit: CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.

Purification: Purified

Pureté: >95 %

Immunogène: Human peripheral blood lymphocytes

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD3

Antigène: CD3

Autre désignation: CD3

NCBI Accession: NM_000733

UniProt: P07766

Pathways: TCR Signaling, Ubiquitin Proteasome Pathway