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CD3 anticorps

GMP Grade CD3 Reactivité: Humain FACS Hôte: Souris Monoclonal OKT3 unconjugated
N° du produit ABIN2704232
  • Antigène Voir toutes CD3 Anticorps
    CD3
    Reactivité
    • 214
    • 97
    • 30
    • 15
    • 15
    • 10
    • 8
    • 8
    • 7
    • 7
    • 3
    • 3
    • 3
    • 2
    • 2
    Humain
    Hôte
    • 249
    • 52
    • 14
    • 13
    • 9
    Souris
    Clonalité
    • 326
    • 7
    Monoclonal
    Conjugué
    • 94
    • 35
    • 30
    • 25
    • 23
    • 13
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CD3 est non-conjugé
    Application
    • 287
    • 91
    • 57
    • 50
    • 45
    • 40
    • 39
    • 24
    • 16
    • 10
    • 9
    • 9
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Attributs du produit
    CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
    Purification
    Purified
    Pureté
    >95 %
    Classe de qualité
    GMP Grade
    Immunogène
    Human peripheral blood lymphocytes
    Clone
    OKT3
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product CD3 Anticorps primaire
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Antigène
    CD3
    Autre désignation
    CD3 (CD3 Produits)
    Synonymes
    anticorps CD3, anticorps AI504783, anticorps CD3epsilon, anticorps T3e, anticorps cd3-gamma, anticorps cd3g, anticorps cd3g-a, anticorps cd3g/d, anticorps cd3gd, anticorps t3g, anticorps CD3e molecule, anticorps CD3d molecule, anticorps CD3 antigen, epsilon polypeptide, anticorps CD3g molecule S homeolog, anticorps CD3E, anticorps CD3D, anticorps Cd3e, anticorps cd3g.S
    Sujet
    CD3ε is a 20kD peptide chain, which together with CD3λ, CD3δ, and CD3ζ, and a T cell receptor (α/β or γ/) form the CD3/T-cell receptor complex. It is a specific marker for T lymphocytes, NK T cells, and some thymocytes. Crosslinking of TCR initiates an intracellular signaling cascade resulting in cellular activation and proliferation. The OKT3 antibody shows potent immunosuppressive properties in vivo and has been proved effective in the treatment of renal, heart, and liver allograft rejection.
    NCBI Accession
    NM_000733
    UniProt
    P07766
    Pathways
    TCR Signaling, Ubiquitin Proteasome Pathway
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