CD4 anticorps

N° du produit ABIN2704265

Cet anticorps anti-CD4 est un anticorps Souris Monoclonal détectant CD4 dans FACS. Adapté pour Humain, Macaque rhésus et Cynomolgus.

Aperçu rapide pour CD4 anticorps (ABIN2704265)

Antigène: CD4

Reactivité: Humain, Macaque rhésus, Cynomolgus

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD4 est non-conjugé

Application: Flow Cytometry (FACS)

Classe de qualité: GMP Grade

Clone: OKT4

Détail du produit anti-CD4 anticorps

Fonction: CD4 Unconjugated Antibody

Attributs du produit: CD4 is a 55kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. It is a specific marker for T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. The OKT4 binds to the D3 domain of CD4 and does not inhibit HIV binding

Purification: Purified

Pureté: >95 %

Immunogène: Human peripheral blood T lymphocytes

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS pH 7.2, 0.1 % (w/v) BSA, 0.09 % (w/v) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur CD4

Antigène: CD4

Autre désignation: CD4

NCBI Accession: NM_000616

UniProt: P01730

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events