CAMLG anticorps
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- Antigène Voir toutes CAMLG Anticorps
- CAMLG (Calcium Modulating Ligand (CAMLG))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CAMLG est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)
- Attributs du produit
- Homo sapiens calcium modulating ligand (CAMLG)
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human CAMLG(NP_001736) produced in HEK293T cell.
- Clone
- 1H3
- Isotype
- IgG2b
- Top Product
- Discover our top product CAMLG Anticorps primaire
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- Indications d'application
- WB 1:2000, IF 1:100, FLOW 1:100,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- CAMLG (Calcium Modulating Ligand (CAMLG))
- Autre désignation
- CAMLG (CAMLG Produits)
- Synonymes
- anticorps MGC53900, anticorps CAML, anticorps AI385748, anticorps Camlg, anticorps Caml, anticorps calcium modulating ligand L homeolog, anticorps calcium modulating ligand, anticorps camlg.L, anticorps CAMLG, anticorps camlg, anticorps Caml, anticorps Camlg
- Sujet
- The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.
- Poids moléculaire
- 32.8 kDa
- ID gène
- 819
- NCBI Accession
- NM_001745
- HGNC
- 819
- Pathways
- EGFR Signaling Pathway
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