EIF4E anticorps

N° du produit ABIN2720089

Détail du produit anti-EIF4E anticorps

Antigène: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EIF4E est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Attributs du produit: Homo sapiens eukaryotic translation initiation factor 4E (EIF4E), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human EIF4E (NP_001959) produced in HEK293T cell.

Clone: 6C3

Isotype: IgG1

Information d'application

Indications d'application: WB 1:500, IHC 1:150,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur EIF4E

Antigène: EIF4E (Eukaryotic Translation Initiation Factor 4E (EIF4E))

Autre désignation: EIF4E (EIF4E Produits)

Synonymes: anticorps AUTS19, anticorps CBP, anticorps EIF4E1, anticorps EIF4EL1, anticorps EIF4F, anticorps eif4e-1, anticorps zgc:86680, anticorps EG668879, anticorps Eif4e-ps, anticorps If4e, anticorps eIF-4E, anticorps 0260/09, anticorps 0587/11, anticorps 0589/11, anticorps 0919/12, anticorps 1004/13, anticorps 2, anticorps 7238, anticorps CG4035, anticorps CT13384, anticorps CT39424, anticorps CT39426, anticorps D-eIF4E, anticorps Dmel\\CG4035, anticorps Eif4E, anticorps Eif4e, anticorps IF4E, anticorps dEif4e, anticorps deIF-4E, anticorps deIF4E, anticorps eIF 4E, anticorps eIF-4E1, anticorps eIF-4E2, anticorps eIF-4EII, anticorps eIF-4e, anticorps eIF4E, anticorps eIF4E-1, anticorps eIF4E-1/2, anticorps eIF4E-2, anticorps eIF4E1, anticorps eIF4EI, anticorps eIF4e, anticorps eif-4E, anticorps eif-4e, anticorps eif4e, anticorps l(3)07238, anticorps l(3)67Af, anticorps l(3)S025007, anticorps l(3)S026009, anticorps l(3)S058711, anticorps l(3)S091912, anticorps cbp, anticorps eif4f, anticorps eif4e1, anticorps eif4el1, anticorps EIF-4E, anticorps zgc:101581, anticorps eukaryotic translation initiation factor 4E, anticorps eukaryotic translation initiation factor 4ea, anticorps Eukaryotic initiation factor 4E, anticorps eucaryotic initiation factor 6, anticorps eukaryotic translation initiation factor 4E L homeolog, anticorps eukaryotic translation initiation factor 4E family member 1B S homeolog, anticorps translation initiation factor eIF4E, anticorps eukaryotic translation initiation factor 4eb, anticorps EIF4E, anticorps eif4ea, anticorps Eif4e, anticorps eIF-4E, anticorps eif6, anticorps eif4e, anticorps eif4e.L, anticorps eif4e1b.S, anticorps LOC100533326, anticorps eif4eb

Sujet: All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). This structure is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A (see MIM 601102), that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G (MIM 600495) (Rychlik et al., 1987 [PubMed 3469651]).

Poids moléculaire: 24.9 kDa

ID gène: 1977

NCBI Accession: NM_001968

HGNC: 1977

Pathways: BCR Signaling