GALE anticorps
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- Antigène Voir toutes GALE Anticorps
- GALE (UDP-Galactose-4-Epimerase (GALE))
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Reactivité
- Humain, Rat, Chien, Singe
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp GALE est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Homo sapiens UDP-galactose-4-epimerase (GALE), transcript variant 1
- Purification
- Purified from mouse ascites fluids by affinity chromatography
- Immunogène
- Full length human recombinant protein of human GALE (NP_000394) produced in HEK293T cell.
- Clone
- 1C4
- Isotype
- IgG1
- Top Product
- Discover our top product GALE Anticorps primaire
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- Indications d'application
- WB 1:500~2000, IHC 1:150,
- Commentaires
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The concentration of the product may vary between diferrent lots.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- GALE (UDP-Galactose-4-Epimerase (GALE))
- Autre désignation
- GALE (GALE Produits)
- Synonymes
- anticorps GALE, anticorps im:7147391, anticorps wu:fb05f01, anticorps zgc:136578, anticorps F15H21.11, anticorps F15H21_11, anticorps REB1, anticorps ROOT EPIDERMAL BULGER1, anticorps ROOT HAIR DEFECTIVE 1, anticorps UDP-GLUCOSE 4-EPIMERASE, anticorps UGE4, anticorps ECK0748, anticorps galD, anticorps JW0742, anticorps SMU.888, anticorps BA5505, anticorps BA5700, anticorps VFA0352, anticorps galE, anticorps 2310002A12Rik, anticorps AI323962, anticorps 1n569, anticorps xgale, anticorps SDR1E1, anticorps UDP-galactose-4-epimerase, anticorps NAD(P)-binding Rossmann-fold superfamily protein, anticorps UDP-galactose 4-epimerase GalE, anticorps UDP-glucose 4-epimerase, anticorps UDP-glucose 4-epimerase GalE, anticorps UDP-glucose/UDP-N-acetylglucosamine 4-epimerase, anticorps galactose-4-epimerase, UDP, anticorps UDP-galactose-4-epimerase L homeolog, anticorps GALE, anticorps gale, anticorps RHD1, anticorps ECs0787, anticorps galE, anticorps galE1, anticorps galE2, anticorps STY0809, anticorps galE-2, anticorps SG0897, anticorps galD, anticorps Ent638_1250, anticorps Gale, anticorps gale.L
- Sujet
- This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
- Poids moléculaire
- 38.1 kDa
- ID gène
- 2582
- NCBI Accession
- NM_000403
- HGNC
- 2582
- Pathways
- Response to Water Deprivation, Cellular Glucan Metabolic Process
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