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CDK5R1 anticorps
CDK5R1
Reactivité: Humain, Souris, Rat
WB, IF, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Détail du produit anti-CDK5R1 anticorps
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Antigène
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CDK5R1
(Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
Reactivité
Toutes les réactivités sur CDK5R1 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur CDK5R1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CDK5R1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CDK5R1 Anticorps
Cet anticorp CDK5R1 est non-conjugé
Application
Tous les applications à travers CDK5R1 Anticorps.
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
This antibody detects endogenous levels of p35 protein. (region surrounding Gln31)
Réactivité croisée (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity Chromatography using epitope-specific immunogen.
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Alternatives
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Information d'application
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Indications d'application
ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Stockage
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conseil sur la manipulation
Avoid repeated freezing and thawing.
Stock
4 °C/-20 °C
Stockage commentaire
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Détails sur CDK5R1
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Antigène
CDK5R1
(Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))
Autre désignation
CDK5R1 (CDK5R1 Produits )
Synonymes
anticorps CDK5P35, anticorps CDK5R, anticorps NCK5A, anticorps p23, anticorps p25, anticorps p35, anticorps p35nck5a, anticorps cdk5r1, anticorps zgc:92814, anticorps CDK5R1, anticorps Cdk5r, anticorps P25/P35, anticorps D11Bwg0379e, anticorps Xp35.1, anticorps cyclin dependent kinase 5 regulatory subunit 1, anticorps cyclin-dependent kinase 5, regulatory subunit 1b (p35), anticorps cyclin-dependent kinase 5 regulatory subunit 1, anticorps S100 calcium binding protein A9, anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35), anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog, anticorps CDK5R1, anticorps cdk5r1b, anticorps Cdk5r1, anticorps S100A9, anticorps cdk5r1.L
Classe de substances
Viral Protein
Sujet
Cyclin dependent kinase-5 (Cdk5), a key regulator of cell cycle progression, was originally isolated on the basis of its structural homology to Cdc2, a wellcharacterized regulator of cell cycle progression. Although Cdk5 is expressed at the highest level in the brain of adult mice, intermediate levels in testis and low or undetectable levels in all other tissues, brain is the only tissue from which Cdk5 can be isolated as an active kinase. These findings may be explained by the cloning and characterization of a Cdk5 regulatory subunit, designated p35. p35 displays a neuronal cell-specific pattern of expression, physically associates with Cdk5 and activates Cdk5 enzymatic activity. p35 is also expressed in many tissues in a truncated form, designated p25.
Poids moléculaire
approx. 38 kDa
ID gène
8851
NCBI Accession
NP_003876
UniProt
Q15078
Pathways
Stem Cell Maintenance , Regulation of Cell Size , Positive Regulation of Endopeptidase Activity
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