CDK5R1 anticorps (N-Term)

N° du produit ABIN6243625

Détail du produit anti-CDK5R1 anticorps

Antigène: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Épitope: AA 30-64, N-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CDK5R1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This CDK5R1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 30-64 amino acids from the N-terminal region of human CDK5R1.

Clone: RB50920

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Détails sur CDK5R1

Antigène: CDK5R1 (Cyclin-Dependent Kinase 5, Regulatory Subunit 1 (p35) (CDK5R1))

Autre désignation: CDK5R1 (CDK5R1 Produits)

Synonymes: anticorps CDK5P35, anticorps CDK5R, anticorps NCK5A, anticorps p23, anticorps p25, anticorps p35, anticorps p35nck5a, anticorps cdk5r1, anticorps zgc:92814, anticorps CDK5R1, anticorps Cdk5r, anticorps P25/P35, anticorps D11Bwg0379e, anticorps Xp35.1, anticorps cyclin dependent kinase 5 regulatory subunit 1, anticorps cyclin-dependent kinase 5, regulatory subunit 1b (p35), anticorps cyclin-dependent kinase 5 regulatory subunit 1, anticorps S100 calcium binding protein A9, anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35), anticorps cyclin-dependent kinase 5, regulatory subunit 1 (p35) L homeolog, anticorps CDK5R1, anticorps cdk5r1b, anticorps Cdk5r1, anticorps S100A9, anticorps cdk5r1.L

Classe de substances: Viral Protein

Sujet: P35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution.

Poids moléculaire: 34060

UniProt: Q15078

Pathways: Stem Cell Maintenance, Regulation of Cell Size, Positive Regulation of Endopeptidase Activity