ATF6B anticorps

N° du produit ABIN272250

Cet anticorps anti-ATF6B Polyclonal Lapin (ABIN272250) détecte spécifiquement ATF6B dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ATF6B anticorps (ABIN272250)

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATF6B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ATF6B anticorps

Specificité: This antibody detects endogenous levels of ATF-6β protein. (region surrounding Ser425)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur ATF6B

Antigène: ATF6B (Activating Transcription Factor 6 beta (ATF6B))

Autre désignation: ATF6 beta

Sujet: ATF-6 is a member of the basic-leucine zipper family of transcription factors. Endoplasmic reticulum stress causes cleavage of transmembrane ATF-6 and transclocation of active ATF-6 to the nucleus. Soluble ATF-6 can exist as either an ATF-6β homodimer or an ATF-6α/β heterodimer. Binding of the ATF-6β homodimer or ATF-6α/β heterodimer to the nuclear transcription factor Y C (NF-YC) induces ER chaperone transcription. Human ATF-6β maps to 1q22-q23 gene locus.Synonyms: ATF-6, Activating transcription factor 6 beta, CREBL1, Creb-rp, Cyclic AMP-dependent transcription factor ATF-6 beta, G13, Protein G13, cAMP response element-binding protein-related protein, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1

Poids moléculaire: approx. 76 kDa

ID gène: 1388

NCBI Accession: NP_001129625

UniProt: Q99941

Pathways: Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction