YWHAB anticorps

N° du produit ABIN272264

Détail du produit anti-YWHAB anticorps

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp YWHAB est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of 14-3-3 beta protein. (region surrounding Gln69)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur YWHAB

Antigène: YWHAB (14-3-3 alpha + beta (YWHAB))

Autre désignation: 14-3-3 Protein beta/alpha (YWHAB Produits)

Synonymes: anticorps GW128, anticorps HS1, anticorps KCIP-1, anticorps YWHAA, anticorps 1300003C17Rik, anticorps wu:fb22g04, anticorps wu:fr86a12, anticorps ywhab, anticorps ywhab2, anticorps zgc:64092, anticorps 14-3-3beta, anticorps fb80c08, anticorps fk41f08, anticorps wu:fb80c08, anticorps wu:fd11d01, anticorps wu:fk41f08, anticorps ywhab1, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog, anticorps tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a, anticorps YWHAB, anticorps Ywhab, anticorps ywhabb, anticorps ywhab.S, anticorps ywhab.L, anticorps ywhaba

Sujet: 14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven isoforms comprise this family of signaling intermediates, denoted 14-3-3 β, γ, ε, ζ, η, θ and σ. 14-3-3 proteins form dimers that present two binding sites for ligand proteins, thereby bringing together two proteins that may not otherwise associate. These ligands largely share a 14-3-3 consensus binding motif and exhibit serine/threonine phosphorylation. 14-3-3 proteins function in broad regulation of these ligand proteins, by cytoplasmic sequestration, occupation of interaction domains and import/export sequences, prevention of degradation, activation/repression of enzymatic activity and facilitation of protein modification, and thus loss of expression contributes to a vast array of pathogenic cellular activities.Synonyms: KCIP-1, Protein 1054, Protein kinase C inhibitor protein 1, YWHAB

Poids moléculaire: approx. 28 kDa

ID gène: 7529

NCBI Accession: NP_003395

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location