MAPK7 anticorps

N° du produit ABIN2725426

L’anticorps anti-MAPK7 Monoclonal Souris est utilisé pour la détection de MAPK7 dans des échantillons de Humain. Il a été validé pour WB, IF et FACS.

Aperçu rapide pour MAPK7 anticorps (ABIN2725426)

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MAPK7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 1G1

Détail du produit anti-MAPK7 anticorps

Attributs du produit: Homo sapiens mitogen-activated protein kinase 7 (MAPK7), transcript variant 3

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human MAPK7(NP_002740) produced in HEK293T cell.

Isotype: IgG1

Information d'application

Indications d'application: WB 1:2000, IF 1:100, FLOW 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MAPK7

Antigène: MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))

Autre désignation: MAPK7

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported.

Poids moléculaire: 88.2 kDa

ID gène: 5598

NCBI Accession: NM_002749

HGNC: 5598

Pathways: Signalisation MAPK, Neurotrophin Signaling Pathway, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling