PDE1B anticorps

N° du produit ABIN2728483

Cet anticorps anti-PDE1B Monoclonal Souris (Clone 1D6) (ABIN2728483) détecte spécifiquement PDE1B dans WB et IF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PDE1B anticorps (ABIN2728483)

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PDE1B est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Clone: 1D6

Détail du produit anti-PDE1B anticorps

Attributs du produit: Homo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:2000, IF 1:100,

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PDE1B

Antigène: PDE1B (phosphodiesterase 1B, Calmodulin-Dependent (PDE1B))

Autre désignation: PDE1B

Sujet: Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).

Poids moléculaire: 61.2 kDa

ID gène: 5153

NCBI Accession: NM_000924

HGNC: 5153

Pathways: Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma