SOCS3 anticorps

N° du produit ABIN2732335

Cité dans 1 publication. Cet anticorps anti-SOCS3 Monoclonal Souris (Clone 3D3) (ABIN2732335) détecte spécifiquement SOCS3 dans WB, IHC, IF et FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour SOCS3 anticorps (ABIN2732335)

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SOCS3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: 3D3

Détail du produit anti-SOCS3 anticorps

Attributs du produit: Homo sapiens suppressor of cytokine signaling 3 (SOCS3)

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogène: Full length human recombinant protein of human SOCS3 (NP_003946) produced in HEK293T cell.

Isotype: IgG2a

Information d'application

Indications d'application: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100

Commentaires:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-SOCS3 (ABIN2732335)

Lin, Wei, Tsai, Wu, Wu, Chen: "Glycosylation-dependent interaction between CD69 and S100A8/S100A9 complex is required for regulatory T-cell differentiation." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 12, pp. 5006-17, (2015) (PubMed).

Détails sur SOCS3

Antigène: SOCS3 (Suppressor of Cytokine Signaling 3 (SOCS3))

Autre désignation: SOCS3

Sujet: This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene is induced by various cytokines, including IL6, IL10, and interferon (IFN)-gamma. The protein encoded by this gene can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development.

Poids moléculaire: 24.6 kDa

ID gène: 9021

NCBI Accession: NM_003955

HGNC: 9021

Pathways: Signalistation JAK/STAT, Response to Growth Hormone Stimulus, Hepatitis C