RUNX2 anticorps (AA 244-258)

N° du produit ABIN2738787

L’anticorps Lapin Polyclonal anti-RUNX2 a été validé pour WB. Il convient pour détecter RUNX2 dans des échantillons de Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Singe, Hamster, Chimpanzé, Gibbon, Orang-Utan et Mouton.

Aperçu rapide pour RUNX2 anticorps (AA 244-258) (ABIN2738787)

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Reactivité: Humain, Souris, Rat, Chien, Cobaye, Cheval, Porc, Lapin, Singe, Hamster, Chimpanzé, Gibbon, Orang-Utan, Mouton

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RUNX2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RUNX2 anticorps

Épitope: AA 244-258

Specificité: Human CBFA1 / RUNX2

Purification: Immunoaffinity purified

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human RUNX2(244-258aa DRLSDLGRIPHPSMR). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Mouse, Ferret, Sheep, Hamster, Elephant, Rabbit, Horse, Pig, Guinea pig, Dog (100%), Turkey, Sparrow, Chicken, Platypus, Lizard (93%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Information d'application

Indications d'application: Approved: WB (0.5 - 1 μg/mL)

Usage: Core binding factor A1(CBFA1/RUNX2) is a runt-like transcription factor essential for osteoblast differentiation. This protein is a member of the RUNX family of transcription factors and has a Runt DNA-binding domain. It is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. D'Souza et al.(1999) indicate a non-redundant role for Cbfa1 in tooth development that may be distinct from that in bone formation. In odontogenesis, Cbfa1 is not involved in the early signaling networks regulating tooth initiation and early morphogenesis but regulates key epithelial-mesenchymal interactions that control advancing morphogenesis and histodifferentiation of the epithelial enamel organ.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Sterile distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS, 2.5 % BSA, 0.025 % sodium azide/thimerosal.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for 1 month or -20°C for longer. Avoid freeze/thaw cycles.

Détails sur RUNX2

Antigène: RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))

Autre désignation: CBFA1 / RUNX2

Sujet: Name/Gene ID: RUNX2

Synonyms: RUNX2, AML3, CCD, CCD1, OSF2, PEBP2A1, PEBP2A2, PEA2-alpha A, PEBP2-alpha A, OSF-2, PEBP2A, PEBP2aA1, CBF-alpha-1, CBFA1, Oncogene AML-3, PEA2aA, PEBP2aA

ID gène: 860