BAFF anticorps

N° du produit ABIN2745513

L’anticorps anti-BAFF Monoclonal Souris est utilisé pour la détection de BAFF dans des échantillons de Souris. Il a été validé pour IP et Func.

Aperçu rapide pour BAFF anticorps (ABIN2745513)

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BAFF est non-conjugé

Application: Immunoprecipitation (IP), Functional Studies (Func)

Clone: Sandy-2

Détail du produit anti-BAFF anticorps

Fonction: anti-BAFF (mouse), mAb (blocking) (Sandy-2)

Specificité: Recognizes mouse BAFF.

Attributs du produit: Monoclonal Antibody. Recognizes mouse BAFF. Isotype: Mouse IgG1. Clone: Sandy-2. Applications: FUNC (Blocking), IP. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.01EU/μg purified protein (LAL test).

Immunogène: Recombinant mouse BAFF.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire:

+4°C

+4°C

Stable for at least 1 year after receipt when stored at +4°C.

Date de péremption: 12 months

Détails sur BAFF

Antigène: BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))

Autre désignation: BAFF

Sujet:

Alternate Names/Synonyms: BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B

Product Description: BAFF is a master regulator of peripheral B cell survival and, together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).

UniProt: Q9WU72

Pathways: Signalisation NF-kappaB, Production of Molecular Mediator of Immune Response