Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

ARHGEF4 anticorps (AA 143-271)

ARHGEF4 Reactivité: Humain WB, FACS Hôte: Souris Monoclonal ARHGEF-08 unconjugated
N° du produit ABIN2749042
  • Antigène Voir toutes ARHGEF4 Anticorps
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Épitope
    • 8
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 143-271
    Reactivité
    • 31
    • 12
    • 9
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 26
    • 4
    • 1
    Souris
    Clonalité
    • 28
    • 3
    Monoclonal
    Conjugué
    • 11
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ARHGEF4 est non-conjugé
    Application
    • 23
    • 17
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody ARHGEF-08 recognizes human intracellular protein ARHGEF4 / ASEF1, approx. 80 kDa guanine nucleotide exchange factor specific for Rac1 and Cdc42. The epitope is located in the rough at the region of SH3 domain.
    Réactivité croisée (Details)
    Human
    Purification
    Purified by protein-A affinity chromatography.
    Pureté
    > 95 % (by SDS-PAGE)
    Immunogène
    Recombinant fragment of human ARHGEF4 (amino acids 143-271)
    Clone
    ARHGEF-08
    Isotype
    IgG1
    Top Product
    Discover our top product ARHGEF4 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
    Autre désignation
    ARHGEF4 (ARHGEF4 Produits)
    Synonymes
    anticorps ARHGEF4, anticorps ASEF, anticorps ASEF1, anticorps GEF4, anticorps STM6, anticorps 9330140K16Rik, anticorps Asef, anticorps ENSMUSG00000070955, anticorps Rho guanine nucleotide exchange factor 4, anticorps uncharacterized LOC100470646, anticorps rho guanine nucleotide exchange factor 4, anticorps Rho guanine nucleotide exchange factor (GEF) 4, anticorps ARHGEF4, anticorps arhg4, anticorps LOC100470646, anticorps LOC100544917, anticorps Arhgef4
    Sujet
    Rho guanine nucleotide exchange factor 4,ARHGEF4 (Rho guanine nucleotide exchange factor 4), also known as ASEF 1 (adenomatous polyposis coli –, stimulated guanine nucleotide exchange factor 1) is an approximately 80 kDa cytoplasmic protein important for growth factor-mediated regulation of cell morphology and migration. Besides N-terminal adenomatous polyposis coli (APC)-binding region (ABR) it contains Dbl homology (DH), pleckstrin homology (PH) and SH3 domains. The SH3 domain inhibits GEF activity of ARHGEF4 by intramolecular interaction with the DH domain, whereas binding of APC stimulates the GEF activity. Activated ARHGEF4 stimulates the small GTPase Cdc42, which leads to decreased cell-cell adherence and enhanced cell migration.,ASEF1, GEF4, STM6
    ID gène
    50649
    UniProt
    Q9NR80
    Pathways
    Neurotrophin Signaling Pathway
Vous êtes ici:
Support technique