C1QB anticorps (C-Term)

N° du produit ABIN2773842

Cet anticorps anti-C1QB est un anticorps Lapin Polyclonal détectant C1QB dans WB et IHC. Adapté pour Humain, Chien et Cheval. Ce Primary Antibody a été cité dans 6+ publications.

Aperçu rapide pour C1QB anticorps (C-Term) (ABIN2773842)

Antigène: C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

Reactivité: Humain, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp C1QB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-C1QB anticorps

Épitope: C-Term

Séquence: AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS IFSGFLLFPD

Homologie: Dog: 92%, Horse: 82%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against C1QB. It was validated on Western Blot and immunohistochemistry.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human C1QB

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 253 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-C1QB (ABIN2773842)

Takamori, Atsuta, Nakamura, Sawase, Koyano, Hara: "Histopathological comparison of the onset of peri-implantitis and periodontitis in rats." dans: Clinical oral implants research, Vol. 28, Issue 2, pp. 163-170, (2016) (PubMed).

Noguchi, Ukai, Kuramoto, Yoshinaga, Nakamura, Takamori, Yamashita, Hara: "The histopathological comparison on the destruction of the periodontal tissue between normal junctional epithelium and long junctional epithelium." dans: Journal of periodontal research, Vol. 52, Issue 1, pp. 74-82, (2016) (PubMed).

Nakatsu, Yoshinaga, Kuramoto, Nagano, Ichimura, Oshino, Yoshimura, Yano, Hara: "Occlusal trauma accelerates attachment loss at the onset of experimental periodontitis in rats." dans: Journal of periodontal research, Vol. 49, Issue 3, pp. 314-22, (2014) (PubMed).

Nagano, Kaneko, Yoshinaga, Ukai, Kuramoto, Nakatsu, Oshino, Ichimura, Hara: "Gram-positive bacteria as an antigen topically applied into gingival sulcus of immunized rat accelerates periodontal destruction." dans: Journal of periodontal research, Vol. 48, Issue 4, pp. 420-7, (2013) (PubMed).

Kuramoto, Yoshinaga, Kaneko, Ukai, Shiraishi, Oshino, Ichimura, Hara: "The formation of immune complexes is involved in the acute phase of periodontal destruction in rats." dans: Journal of periodontal research, Vol. 47, Issue 4, pp. 455-62, (2012) (PubMed).

Yoshinaga, Ukai, Kaneko, Nakatsu, Shiraishi, Kuramoto, Oshino, Ichimura, Hara: "Topical application of lipopolysaccharide into gingival sulcus promotes periodontal destruction in rats immunized with lipopolysaccharide." dans: Journal of periodontal research, Vol. 47, Issue 5, pp. 674-80, (2012) (PubMed).

Détails sur C1QB

Antigène: C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))

Autre désignation: C1QB

Sujet: C1QB is a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. C1QB is the B-chain polypeptide of human complement subcomponent C1q.This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q.
Alias Symbols: -
Protein Interaction Partner: IL32, EED, FN1, EDA2R, RELA, MYOC, PTX3, C1R, HRG, DEFA1, C1QC, C1QA,
Protein Size: 253

Poids moléculaire: 27 kDa

ID gène: 713

NCBI Accession: NM_000491, NP_000482

UniProt: P02746

Pathways: Système du Complément