Peroxiredoxin 1 anticorps (N-Term)
Aperçu rapide pour Peroxiredoxin 1 anticorps (N-Term) (ABIN2773920)
Antigène
Voir toutes Peroxiredoxin 1 (PRDX1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- SSGNAKIGHP APNFKATAVM PDGQFKDISL SDYKGKYVVF FFYPLDFTFV
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Attributs du produit
- This is a rabbit polyclonal antibody against PRDX1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human PRDX1
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 199 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Peroxiredoxin 1 (PRDX1)
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Autre désignation
- PRDX1
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Sujet
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PRDX1 is a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. It may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein may play an antioxidant protective role in cells, and may contribute to the antiviral activity of CD8(+) T-cells. This protein may have a proliferative effect and play a role in cancer development or progression. Three transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: MSP23, NKEFA, PAG, PAGA, PAGB, PRX1, TDPX2, PRXI
Protein Interaction Partner: FUS, UBC, MDM2, RPA3, RPA2, RPA1, SUZ12, CACYBP, HECTD1, PRDX2, PRKDC, PPP2R5D, METTL1, PARK2, YWHAQ, VHL, EGFR, CDK2, RAD52, MPG, US3, SH2D1B, LUC7L, HCVgp1, PRDX4, IQCB1, BTRC, UBL4A, VCAM1, SMARCD1, FN1, DAB2, ADH5, ABL1, MYD88, MYC, ITGA4, TIPIN, EIF4
Protein Size: 199 -
Poids moléculaire
- 22 kDa
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ID gène
- 5052
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NCBI Accession
- NM_002574, NP_002565
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UniProt
- Q06830
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Pathways
- Signalisation p53, EGFR Signaling Pathway, CXCR4-mediated Signaling Events
Antigène
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