SETMAR anticorps (C-Term)

N° du produit ABIN2773983

Cet anticorps Lapin Polyclonal détecte spécifiquement SETMAR dans WB. Il présente une réactivité avec des échantillons de Humain et Boeuf (Vache).

Aperçu rapide pour SETMAR anticorps (C-Term) (ABIN2773983)

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Reactivité: Humain, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SETMAR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SETMAR anticorps

Épitope: C-Term

Fonction: SETMAR Antibody - C-terminal region

Séquence: FLQGKRFHNQ QDAENAFQEF VESQSTDFYA TGINQLISRW QKCVDCNGSY

Homologie: Cow: 100%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against SETMAR. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP51245-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur SETMAR

Antigène: SETMAR (SET Domain and Mariner Transposase Fusion Gene (SETMAR))

Autre désignation: SETMAR

Sujet:

Background Information: This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

Gene Name: SET domain and mariner transposase fusion gene

Alternative Symbols: Mar1, METNASE

Protein Name: Histone-lysine N-methyltransferase Ensembl ENSP00000403145

Poids moléculaire: 59kDa

ID gène: 6419

NCBI Accession: NP_001230652

UniProt: E7EN68

Pathways: Positive Regulation of Response to DNA Damage Stimulus