APH1B anticorps (C-Term)

N° du produit ABIN2774063

L’anticorps anti-APH1B Polyclonal Lapin est utilisé pour la détection de APH1B dans des échantillons de Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye et Cheval. Il a été validé pour WB.

Aperçu rapide pour APH1B anticorps (C-Term) (ABIN2774063)

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Reactivité: Humain, Souris, Rat, Lapin, Boeuf (Vache), Chien, Cobaye, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APH1B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-APH1B anticorps

Épitope: C-Term

Fonction: APH1B Antibody - C-terminal region

Séquence: YYGINLASAF IILVLMGTWA FLAAGGSCRS LKLCLLCQDK NFLLYNQRSR

Homologie: Cow: 77%, Dog: 85%, Guinea Pig: 92%, Horse: 77%, Human: 100%, Mouse: 92%, Rabbit: 85%, Rat: 92%

Attributs du produit: This is a rabbit polyclonal antibody against APH1B. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53808-100UG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Détails sur APH1B

Antigène: APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))

Autre désignation: APH1B

Sujet:

Targeted Subunit: APH-1B

Background Information: This gene encodes a multi-pass transmembrane protein that is a functional component of the gamma-secretase complex, which also contains presenilin and nicastrin. This protein represents a stabilizing cofactor for the presenilin holoprotein in the complex. The gamma-secretase complex catalyzes the cleavage of integral proteins such as notch receptors and beta-amyloid precursor protein.

Gene Name: Anterior pharynx defective 1 homolog B (C. elegans)

Alternative Symbols: PSFL, APH-1B, PRO1328, TAAV688

Protein Name: Gamma-secretase subunit APH-1B

Poids moléculaire: 23kDa

ID gène: 83464

NCBI Accession: NP_001139118

UniProt: Q564N3

Pathways: Signalisation Notch, Neurotrophin Signaling Pathway