Hexokinase 2 anticorps (N-Term)
-
- Antigène Voir toutes Hexokinase 2 (HK2) Anticorps
- Hexokinase 2 (HK2)
-
Épitope
- N-Term
-
Reactivité
- Humain, Souris, Rat, Chien, Cheval, Lapin, Boeuf (Vache), Cobaye, Poisson zèbre (Danio rerio)
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp Hexokinase 2 est non-conjugé
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GTEHGEFLAL DLGGTNFRVL WVKVTDNGLQ KVEMENQIYA IPEDIMRGSG
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Attributs du produit
- This is a rabbit polyclonal antibody against HK2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human HK2
- Top Product
- Discover our top product HK2 Anticorps primaire
-
-
- Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
- Commentaires
-
Antigen size: 917 AA
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Antigène
- Hexokinase 2 (HK2)
- Autre désignation
- HK2 (HK2 Produits)
- Synonymes
- anticorps HKII, anticorps HXK2, anticorps AI642394, anticorps hexokinase-2, anticorps fi09d05, anticorps fi17h06, anticorps wu:fi09d05, anticorps wu:fi17h06, anticorps wu:fi31b04, anticorps zgc:55926, anticorps HK2, anticorps ARABIDOPSIS THALIANA HEXOKINASE 2, anticorps ATHXK2, anticorps F6F22.11, anticorps F6F22_11, anticorps HEXOKINASE 2, anticorps hexokinase 2, anticorps StHK2, anticorps hexokinase 2, anticorps hexokinase-2, anticorps hexokinase 2 L homeolog, anticorps HK2, anticorps Hk2, anticorps hk2, anticorps HXK2, anticorps LOC100032849, anticorps hk2.L, anticorps hxk2, anticorps LOC102577690
- Sujet
-
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. HK2 (hexokinase 2) is the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this protein is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. This gene encodes hexokinase 2, the predominant form found in skeletal muscle. It localizes to the outer membrane of mitochondria. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-348 AI278414.1 4-351 349-732 CB160837.1 11-394 c 733-1006 BM912287.1 1-274 c 1007-1333 AI085541.1 1-327 c 1334-1477 AW134604.1 8-151 1478-4058 AF148513.1 1-2581 4059-5498 BC064369.1 2575-4014 5499-5615 BM706373.1 303-419 5616-7109 BC064369.1 4130-5623
Alias Symbols: DKFZp686M1669, HKII, HXK2
Protein Interaction Partner: UBQLN1, MAGEA12, SUMO2, SUMO3, UBC, EGFR, rev, H2AFV, WDR61, ARIH2, PDLIM1, PYGL, NUBP1, IPO5, HEXB, FNTA, FBXO6, PARK2, UBD, ITGA4, NUDCD3, UBQLN4, SLC2A4, ELAVL1, PTGDS, ZBTB17, PRKCE, IGFBP4,
Protein Size: 917 - Poids moléculaire
- 102 kDa
- ID gène
- 3099
- NCBI Accession
- NM_000189, NP_000180
- UniProt
- P52789
- Pathways
- Signalisation PI3K-Akt, Carbohydrate Homeostasis, L'effet Warburg
-