CD70 anticorps (N-Term)

N° du produit ABIN2774311

Détail du produit anti-CD70 anticorps

Antigène: CD70 (CD70 Molecule (CD70))

Épitope: N-Term

Reactivité: Humain, Boeuf (Vache), Lapin, Cheval, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD70 est non-conjugé

Application: Western Blotting (WB)

Séquence: VICLVVCIQR FAQAQQQLPL ESLGWDVAEL QLNHTGPQQD PRLYWQGGPA

Homologie: Cow: 85%, Guinea Pig: 85%, Horse: 77%, Human: 100%, Rabbit: 85%

Attributs du produit: This is a rabbit polyclonal antibody against CD70. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 193 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur CD70

Antigène: CD70 (CD70 Molecule (CD70))

Autre désignation: CD70 (CD70 Produits)

Synonymes: anticorps CD27LG, anticorps Cd27l, anticorps Tnfsf7, anticorps CD27L, anticorps TNFSF7, anticorps CD70 antigen, anticorps CD70 molecule, anticorps Cd70 molecule, anticorps Cd70, anticorps CD70

Sujet: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Alias Symbols: CD27L, CD27LG, TNFSF7
Protein Interaction Partner: UBC, CD27, ELAVL1,
Protein Size: 193

Poids moléculaire: 21 kDa

ID gène: 970

NCBI Accession: NM_001252, NP_001243

UniProt: P32970

Pathways: Cancer Immune Checkpoints