TNIP1 anticorps (C-Term)

N° du produit ABIN2774321

L’anticorps Lapin Polyclonal anti-TNIP1 a été validé pour WB. Il convient pour détecter TNIP1 dans des échantillons de Humain, Cheval et Chien.

Aperçu rapide pour TNIP1 anticorps (C-Term) (ABIN2774321)

Antigène: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Reactivité: Humain, Cheval, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TNIP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TNIP1 anticorps

Épitope: C-Term

Séquence: NSRLFHLPEY TWRLPCGGVR NPNQSSQVMD PPTARPTEPE SPKNDREGPQ

Homologie: Dog: 92%, Horse: 86%, Human: 100%

Attributs du produit: This is a rabbit polyclonal antibody against TNIP1. It was validated on Western Blot.

Purification: Affinity Purified

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 636 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TNIP1

Antigène: TNIP1 (TNFAIP3 Interacting Protein 1 (TNIP1))

Autre désignation: TNIP1

Sujet: TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.
Alias Symbols: ABIN-1, KIAA0113, NAF1, VAN, nip40-1
Protein Interaction Partner: HDDC3, MAGEB18, CFAP53, TXLNA, CCDC112, MOB3C, SYT6, TCEANC2, MOB1B, MAP1LC3A, NIFK, FAM161A, MAP1LC3B, TNIP3, SNIP1, CDIP1, NME7, MAGEH1, GABARAPL2, PNKP, MORF4L1, RALBP1, ZNHIT1, NDC80, TNIP1, OPTN, MORF4L2, AP1M1, TAX1BP1, ZBTB25, UBC, TNFAIP3, TCEA2,
Protein Size: 636

Poids moléculaire: 70 kDa

ID gène: 10318

NCBI Accession: NM_006058, NP_006049

UniProt: Q15025

Pathways: Activation of Innate immune Response