MEF2C anticorps (Middle Region)

N° du produit ABIN504660

Cet anticorps anti-MEF2C Polyclonal Lapin (ABIN504660) détecte spécifiquement MEF2C dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Porc, Poisson zèbre (Danio rerio), Chien, Cheval et Lapin.

Aperçu rapide pour MEF2C anticorps (Middle Region) (ABIN504660)

Antigène: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Reactivité: Humain, Souris, Rat, Porc, Poisson zèbre (Danio rerio), Chien, Cheval, Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MEF2C est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MEF2C anticorps

Épitope: Middle Region

Séquence: PPSALSQLGA CTSTHLSQSS NLSLPSTQSL NIKSEPVSPP RDRTTTPSRY

Réactivité croisée: Chien, Poulet, Humain, Souris, Porc, Rat (Rattus)

Homologie: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Attributs du produit: This is a rabbit polyclonal antibody against MEF2C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MEF2C

Information d'application

Indications d'application: WB Suggested Anti-MEF2C Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: COLO205 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 473 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur MEF2C

Antigène: MEF2C (Myocyte Enhancer Factor 2C (MEF2C))

Autre désignation: MEF2C

Sujet: MEF2C is a transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. MEF2C controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. MEF2C may also be involved in neurogenesis and in the development of cortical architecture. Isoform 3 and isoform 4, which lack the repressor domain, are more active than isoform 1 and isoform 2.
Alias Symbols: C5DELq14.3, DEL5q14.3
Protein Interaction Partner: PLA2G12A, UBC, ASCL1, SUMO1, HDAC7, HDAC5, HDAC4, MYOD1, IFRD1, NCOA2, SIRT1, HDAC9, COPS5, YWHAZ, SPTBN1, MAPK7, EPAS1, MAPK14, VGLL2, VGLL4, TWIST2, GATA4, SOX18, EP300, SMAD2, MEF2D, MEF2C, NOTCH1, TEAD1, SP1, CCNB1, CDK1, CSNK2A1, MYOG,
Protein Size: 473

Poids moléculaire: 51 kDa

ID gène: 4208

NCBI Accession: NM_002397, NP_002388

UniProt: Q06413

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, BCR Signaling