UBR2 anticorps (C-Term)

N° du produit ABIN2774729

Détail du produit anti-UBR2 anticorps

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBR2 est non-conjugé

Application: Western Blotting (WB)

Séquence: GLKLLSWLGS IIGYSDGLRR ILCQVGLQEG PDGENSSLVD RLMLSDSKLW

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 91%

Attributs du produit: This is a rabbit polyclonal antibody against UBR2. It was validated on Western Blot.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C-terminal region of Human UBR2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBR2

Antigène: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Autre désignation: UBR2 (UBR2 Produits)

Synonymes: anticorps ba49a4.1, anticorps si:ch211-239i4.2, anticorps C6orf133, anticorps RP3-392M17.3, anticorps bA49A4.1, anticorps dJ242G1.1, anticorps dJ392M17.3, anticorps 9930021A08Rik, anticorps AI462103, anticorps AW540746, anticorps E130209G04Rik, anticorps mKIAA0349, anticorps ubiquitin protein ligase E3 component n-recognin 2, anticorps ubiquitin protein ligase E3 component n-recognin 2 S homeolog, anticorps UBR2, anticorps ubr2, anticorps ubr2.S, anticorps Ubr2

Sujet: Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.
Protein Interaction Partner: vif, UBC, UBE2H, RECQL4, HIST1H2BG, HIST2H2AC, TIRAP, UBE2Z, UBXN1, UBXN7, FAF2, FAF1, UBE2B, MYC, HNRNPA1,
Protein Size: 439

Poids moléculaire: 48 kDa

ID gène: 23304