SYVN1 anticorps (Middle Region)

N° du produit ABIN2774800

L’anticorps Lapin Polyclonal anti-SYVN1 a été validé pour WB. Il convient pour détecter SYVN1 dans des échantillons de Humain, Souris, Rat, Cheval, Chien, Boeuf (Vache), Cobaye, Lapin et Saccharomyces cerevisiae.

Aperçu rapide pour SYVN1 anticorps (Middle Region) (ABIN2774800)

Antigène: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Reactivité: Humain, Souris, Rat, Cheval, Chien, Boeuf (Vache), Cobaye, Lapin, Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SYVN1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SYVN1 anticorps

Épitope: Middle Region

Séquence: QGLLPPFPPG MFPLWPPMGP FPPVPPPPSS GEAVAPPSTS AALSRPSGAA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%

Attributs du produit: This is a rabbit polyclonal antibody against SYVN1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SYVN1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 616 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur SYVN1

Antigène: SYVN1 (Synovial Apoptosis Inhibitor 1, Synoviolin (SYVN1))

Autre désignation: SYVN1

Sujet: SYVN1 is a protein involved in endoplasmic reticulum (ER)-associated degradation. The protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins.This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. This gene and the mitochondrial ribosomal protein L49 gene use in their respective 3' UTRs some of the same genomic sequence. Sequence analysis identified two transcript variants that encode different isoforms.
Alias Symbols: HRD1, KIAA1810, MGC40372
Protein Interaction Partner: Rer1, OS9, SEL1L, STXBP5L, UBC, SYVN1, DERL2, HEY2, HEY1, USP19, Ube2g2, MARCH6, VCP, YOD1, ATXN3, DERL1, HERPUD1, TP53, BSG, ASGR1, GPR37, UBE2D3, UBE2D2, USP7, ATN1, APOB, ERLEC1, UBXN8, SHH, ERN1, ASGR2, SARAF, FAM8A1, TYR, AUP1, ERLIN2, SGK1, ATP6AP1,
Protein Size: 616

Poids moléculaire: 67 kDa

ID gène: 84447

NCBI Accession: NM_032431, NP_115807

UniProt: Q86TM6

Pathways: ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling