STUB1 anticorps (C-Term)

N° du produit ABIN2774917

Cet anticorps Lapin Polyclonal détecte spécifiquement STUB1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval et Poisson zèbre (Danio rerio).

Aperçu rapide pour STUB1 anticorps (C-Term) (ABIN2774917)

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Chien, Cheval, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STUB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-STUB1 anticorps

Épitope: C-Term

Séquence: VDEKRKKRDI PDYLCGKISF ELMREPCITP SGITYDRKDI EEHLQRVGHF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Attributs du produit: This is a rabbit polyclonal antibody against STUB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the C terminal region of human STUB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 303 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur STUB1

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Autre désignation: STUB1

Sujet: STUB1 modulates the activity of several chaperone complexes, including Hsp70, Hsc70 and Hsp90. It has E3 ubiquitin-protein ligase activity and targets misfolded chaperone substrates towards proteasomal degradation. STUB1 mediates transfer of non-canonical short ubiquitin chains to HSPA8 that have no effect on HSPA8 degradation.
Alias Symbols: CHIP, HSPABP2, NY-CO-7, SDCCAG7, UBOX1
Protein Interaction Partner: HSP90AA1, HSPA8, PCSK9, OLFM3, ATCAY, CCL28, UBE2Q1, TXN2, RUSC1, HSPA1B, FMR1, ERN1, STUB1, UBE2V1, UBE2N, UBE2D3, UBE2D1, UBC, TP53, MAPT, MAP3K11, SNAI2, BAG1, HSPA4L, CDC37, DNAJB6, BAG2, BAG3, BAG4, MLF2, HSP90AB1, HSPA4, HSPA2, HSPA1L, ENDOG, TXLNG,
Protein Size: 303

Poids moléculaire: 35 kDa

ID gène: 10273

NCBI Accession: NM_005861, NP_005852

UniProt: Q9UNE7

Pathways: Regulation of Hormone Metabolic Process, Response to Water Deprivation