STUB1 anticorps (AA 51-303)

N° du produit ABIN5693017

Détail du produit anti-STUB1 anticorps

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Épitope: AA 51-303

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STUB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for STUB1 detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Immunogène: E. coli-derived human STUB1 recombinant protein (Position: R51-Y303).

Information d'application

Indications d'application:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Détails sur STUB1

Antigène: STUB1 (STIP1 Homology and U-Box Containing Protein 1 (STUB1))

Autre désignation: STUB1 (STUB1 Produits)

Synonymes: anticorps CHIP, anticorps HSPABP2, anticorps NY-CO-7, anticorps SDCCAG7, anticorps UBOX1, anticorps 0610033N24Rik, anticorps 2210017D18Rik, anticorps 2310040B03Rik, anticorps AW046544, anticorps Chip, anticorps wu:fc22f04, anticorps zgc:56076, anticorps STUB1, anticorps chip, anticorps ATCHIP, anticorps CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN, anticorps carboxyl terminus of HSC70-interacting protein, anticorps STIP1 homology and U-box containing protein 1, anticorps STIP1 homology and U-Box containing protein 1, anticorps STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase L homeolog, anticorps STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase, anticorps STIP1 homology and U box-containing protein 1, anticorps carboxyl terminus of HSC70-interacting protein, anticorps STUB1, anticorps Stub1, anticorps stub1, anticorps stub1.L, anticorps LOC100282870, anticorps CHIP

Sujet:

Synonyms: E3 ubiquitin-protein ligase CHIP

Tissue Specificity: Highly expressed in skeletal muscle, heart, pancreas, brain and placenta. Detected in kidney, liver and lung.

Background: STUB1 (STIP1 homology and U-Box containing protein 1), also known as CHIP (C terminus of HSC70-Interacting Protein), is a human gene. This gene encodes a protein containing tetratricopeptide repeat and a U-box that functions as a ubiquitin ligase/cochaperone. The encoded protein binds to and ubiquitinates shock cognate 71 kDa protein (Hspa8) and DNA polymerase beta (Polb), among other targets. Mutations in this gene cause spinocerebellar ataxia, autosomal recessive 16. Alternative splicing results in multiple transcript variants. There is a pseudogene for this gene on chromosome 2.

Pathways: Regulation of Hormone Metabolic Process, Response to Water Deprivation