UBE2C anticorps (Middle Region)

N° du produit ABIN2774934

Détail du produit anti-UBE2C anticorps

Antigène: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Cheval, Lapin, Cobaye

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UBE2C est non-conjugé

Application: Western Blotting (WB)

Séquence: QGNICLDILK EKWSALYDVR TILLSIQSLL GEPNIDSPLN THAAELWKNP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against UBE2C. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human UBE2C

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 179 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur UBE2C

Antigène: UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))

Autre désignation: UBE2C (UBE2C Produits)

Synonymes: anticorps LOC458287, anticorps UBCH10, anticorps dJ447F3.2, anticorps 1110015A16Rik, anticorps D2Ertd695e, anticorps im:7137135, anticorps zgc:123190, anticorps ubiquitin conjugating enzyme E2 C, anticorps ubiquitin-conjugating enzyme E2C, anticorps ubiquitin conjugating enzyme E2 C L homeolog, anticorps ubiquitin conjugating enzyme E2 C S homeolog, anticorps UBE2C, anticorps NAEGRDRAFT_82946, anticorps ube2c.L, anticorps Ube2c, anticorps ube2c.S, anticorps ube2c

Sujet: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2C is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for the destruction of mitotic cyclins and for cell cycle progression. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: UBCH10, dJ447F3.2
Protein Interaction Partner: ANAPC11, FZR1, KLHL2, UBE2C, PCGF3, UBC, MAPK7, UBA1, BAG3, TNNC1, CXCR1, Rag1, TTC9C, UNK, ZFYVE19, UBQLN4, UBXN1, UBQLN1, UBXN7, TTLL12, SEC24A, AHCYL1, SSSCA1, YAP1, UBE4B, USP34, ZRANB2, ATP6V1F, USP9X, UBE2V1, UBE2B, TYMS, TRIP6, PSMC6, PSMA5, PPM1G,
Protein Size: 179

Poids moléculaire: 20 kDa

ID gène: 11065

NCBI Accession: NM_007019, NP_008950

UniProt: O00762

Pathways: Ubiquitin Proteasome Pathway