DDX42 anticorps (N-Term)
Aperçu rapide pour DDX42 anticorps (N-Term) (ABIN2775212)
Antigène
Voir toutes DDX42 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- N-Term
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Séquence
- PLEAFMAEVE DQAARDMKRL EEKDKERKNV KGIRDDIEEE DDQEAYFRYM
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
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Attributs du produit
- This is a rabbit polyclonal antibody against DDX42. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the N terminal region of human DDX42
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Indications d'application
- Optimal working dilutions should be determined experimentally by the investigator.
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Commentaires
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Antigen size: 938 AA
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDX42 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42 (DDX42))
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Autre désignation
- DDX42
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Sujet
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DDX42 is a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. DDX42 is a ATP-dependent RNA helicase. DDX42 binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. It also mediates RNA duplex formation thereby displacing the single-strand RNA binding protein.This gene encodes a member of the Asp-Glu-Ala-Asp (DEAD) box protein family. Members of this protein family are putative RNA helicases, and are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: FLJ43179, RHELP, RNAHP, SF3b125
Protein Interaction Partner: FUS, UBC, SUMO1, EED, SHFM1, FBXO25, LMNA, PRPF19, U2SURP, SF3A1, SF3B4, SNRPC, ITGA4, DHX15, PIN4, KAL1, EPRS, APP, PHF20, NOSIP, RPL36, FOXJ3, TCERG1, SYNCRIP, RPS6KA4, SUMO3, ISG15, SIRT7, SF3A2, MEPCE, RUVBL2, RUVBL1, RECQL5, SF3B1,
Protein Size: 938 -
Poids moléculaire
- 103 kDa
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ID gène
- 11325
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NCBI Accession
- NM_007372, NP_031398
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UniProt
- Q86XP3
Antigène
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