RAD23A anticorps (N-Term)

N° du produit ABIN2775295

L’anticorps Lapin Polyclonal anti-RAD23A a été validé pour WB et IHC. Il convient pour détecter RAD23A dans des échantillons de Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye et Boeuf (Vache).

Aperçu rapide pour RAD23A anticorps (N-Term) (ABIN2775295)

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Reactivité: Humain, Souris, Rat, Chien, Cheval, Lapin, Cobaye, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD23A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-RAD23A anticorps

Épitope: N-Term

Séquence: VPSSGSSGRE EDAASTLVTG SEYETMLTEI MSMGYERERV VAALRASYNN

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Attributs du produit: This is a rabbit polyclonal antibody against RAD23A. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the N terminal region of human RAD23A

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 363 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur RAD23A

Antigène: RAD23A (RAD23 Homolog A (RAD23A))

Autre désignation: RAD23A

Sujet: RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: USP25, ZBTB44, TRIP6, TRAF5, TRAF2, ZBTB8A, ANKRD40, FAM188A, TRIM54, NGLY1, CEP250, CEP76, UBC, SHFM1, vpr, XPC, DCTPP1, OGFOD1, UBA6, UBE2R2, TRNT1, HERC4, NT5C2, FKBP9, PCNA, HEXA, CDC34, GNPDA1, GTF3C4, USP5, WARS, TBCE, PYGL, PARP1, SH3RF2, PARK2, SQ
Protein Size: 363

Poids moléculaire: 40 kDa

ID gène: 5886

NCBI Accession: NM_005053, NP_005044

UniProt: P54725

Pathways: Réparation de l'ADN