SLC1A5 anticorps (Middle Region)

N° du produit ABIN2775316

Détail du produit anti-SLC1A5 anticorps

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Mouton, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC1A5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Séquence: FGVALRKLGP EGELLIRFFN SFNEATMVLV SWIMWYAPVG IMFLVAGKIV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SLC1A5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC1A5

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 541 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC1A5 (ABIN2775316)

Qiu, Qin, Luo, Zhang, Sun, Jiao, Li, Yin: "Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine." dans: PLoS ONE, Vol. 11, Issue 9, pp. e0162475, (2016) (PubMed).

Zhu, Lin, Dai, Zhou, Li, Yuan, Wu, Wu, Wang: "L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells." dans: Amino acids, Vol. 47, Issue 10, pp. 2185-97, (2015) (PubMed).

Bungard, McGivan: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." dans: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, (2005) (PubMed).

Détails sur SLC1A5

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Autre désignation: SLC1A5 (SLC1A5 Produits)

Synonymes: anticorps aaat, anticorps asct2, anticorps atbo, anticorps m7v1, anticorps m7vs1, anticorps r16, anticorps rdrc, anticorps AAAT, anticorps ASCT2, anticorps ATBO, anticorps M7V1, anticorps M7VS1, anticorps R16, anticorps RDRC, anticorps Slc1a7, anticorps Asct2, anticorps H4-ASCT2, anticorps solute carrier family 1 (neutral amino acid transporter), member 5, anticorps solute carrier family 1 member 5 S homeolog, anticorps solute carrier family 1 member 5, anticorps slc1a5, anticorps slc1a5.S, anticorps SLC1A5, anticorps Slc1a5

Sujet: SLC1A5 has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.
Alias Symbols: AAAT, ASCT2, ATBO, FLJ31068, M7V1, M7VS1, R16, RDRC
Protein Interaction Partner: UBC, FUS, LGR4, ADRB2, ALB, PAXIP1, ECT2, MCU, MRPS35, CYB5R3, CAND1, CUL3, USP50, USP19, TBC1D17, ERVW-1, NEK6, MPDU1, LGALS9,
Protein Size: 541

Poids moléculaire: 56 kDa

ID gène: 6510

NCBI Accession: NM_005628, NP_005619

UniProt: Q71UA6

Pathways: Dicarboxylic Acid Transport, L'effet Warburg