SLC1A5 anticorps (Middle Region)

N° du produit ABIN2775316

Cité dans 3 publications. Cet anticorps anti-SLC1A5 Polyclonal Lapin (ABIN2775316) détecte spécifiquement SLC1A5 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Mouton, Cobaye, Lapin et Poisson zèbre (Danio rerio).

Aperçu rapide pour SLC1A5 anticorps (Middle Region) (ABIN2775316)

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Cheval, Porc, Mouton, Cobaye, Lapin, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC1A5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-SLC1A5 anticorps

Épitope: Middle Region

Fonction: SLC1A5 Antibody - middle region

Séquence: FGVALRKLGP EGELLIRFFN SFNEATMVLV SWIMWYAPVG IMFLVAGKIV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Attributs du produit: This is a rabbit polyclonal antibody against SLC1A5. It was validated on Western Blot and immunohistochemistry.

Purification: Protein A purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human SLC1A5

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8112037

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: prevent freeze-thaw cycles

Stock: 4 °C,-20 °C

Stockage commentaire: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Références pour anticorps anti-SLC1A5 (ABIN2775316)

Qiu, Qin, Luo, Zhang, Sun, Jiao, Li, Yin: "Protein Restriction with Amino Acid-Balanced Diets Shrinks Circulating Pool Size of Amino Acid by Decreasing Expression of Specific Transporters in the Small Intestine." dans: PLoS ONE, Vol. 11, Issue 9, pp. e0162475, (2016) (PubMed).

Zhu, Lin, Dai, Zhou, Li, Yuan, Wu, Wu, Wang: "L-Glutamine deprivation induces autophagy and alters the mTOR and MAPK signaling pathways in porcine intestinal epithelial cells." dans: Amino acids, Vol. 47, Issue 10, pp. 2185-97, (2015) (PubMed).

Bungard, McGivan: "Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers." dans: Archives of biochemistry and biophysics, Vol. 443, Issue 1-2, pp. 53-9, (2005) (PubMed).

Détails sur SLC1A5

Antigène: SLC1A5 (Solute Carrier Family 1 Member 5 (SLC1A5))

Autre désignation: SLC1A5

Sujet:

Background Information: SLC1A5 has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. It acts as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.

Gene Name: Solute carrier family 1 (neutral amino acid transporter), member 5

Alternative Symbols: R16, AAAT, ATBO, M7V1, RDRC, ASCT2, M7VS1

Protein Name: Neutral amino acid transporter EMBL AAD09814.1

Poids moléculaire: 57 kDa

ID gène: 6510

NCBI Accession: NP_005619

UniProt: Q71UA6

Pathways: Dicarboxylic Acid Transport, L'effet Warburg