Mesothelin anticorps (Middle Region)

N° du produit ABIN2775327

L’anticorps Lapin Polyclonal anti-Mesothelin a été validé pour WB. Il convient pour détecter Mesothelin dans des échantillons de Humain, Souris, Rat, Boeuf (Vache), Cobaye, Porc, Chien et Cheval.

Aperçu rapide pour Mesothelin anticorps (Middle Region) (ABIN2775327)

Antigène: Mesothelin (MSLN)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Porc, Chien, Cheval

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mesothelin est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Mesothelin anticorps

Épitope: Middle Region

Séquence: QKLLGPHVEG LKAEERHRPV RDWILRQRQD DLDTLGLGLQ GGIPNGYLVL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 93%

Attributs du produit: This is a rabbit polyclonal antibody against MSLN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human MSLN

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 622 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur Mesothelin

Antigène: Mesothelin (MSLN)

Autre désignation: MSLN

Sujet: An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin.An antibody that reacts with ovarian cancers and mesotheliomas was used to isolate a cell surface antigen named mesothelin. Although the function of mesothelin is unknown, it may play a role in cellular adhesion and is present on mesothelium, mesotheliomas, and ovarian cancers. This gene encodes a preproprotein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Alternative splicing results in multiple transcript variants.
Alias Symbols: CAK1, MPF, SMR, SMRP
Protein Interaction Partner: RSG1, MRPL1, RNMTL1, MRPL16, ZBTB43, MRPL28, LAMTOR3, RALA, NDUFB9, NDUFB5, MPV17, ATP6V1A, MUC16,
Protein Size: 622

Poids moléculaire: 32 kDa

ID gène: 10232

NCBI Accession: NM_005823, NP_005814

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process